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About Rogaine, Finasteride and Azole Alopecia Drugs

By far the most promising approaches to the treatment of baldness in men are drug therapies, such as topical Rogaine and finasteride administered systemically. Mild to moderate androgenic alopecia in women can be treated with antiandrogens and/or topical Rogaine with good results in many cases. Two US Food and Drug Administration approved hair-loss drugs Minoxidil and finasteride - are safe and effective for controlling male pattern baldness with long-term daily use [order online propecia]. Azole drugs such as miconazole, clotrimazole, and ketoconazole are fungistatic, limiting fungal growth but depending on epidermal turnover to shed the still-living fungus from the skin surface.One hundred male patients with Androgenic alopecia were enrolled in study, designed to evaluate and compare the efficacy of oral finasteride (1 mg per day), topical 2% minoxidil solution and topical 2% ketoconazole shampoo alone and in combination. At the end of one year, hair growth was observed in all the groups with best results recorded with a combination of finasteride and minoxidil, then finasteride with topical ketoconazole, then oral finasteride, then minoxidil alone. Subjects receiving finasteride alone or in combination with Rogaine or ketoconazole showed statistically significant improvement over Rogaine only recipients. No significant side-effects related to the drugs were observed.

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Topically administered Rogaine is labeled for the treatment of androgenic alopecia in women. Corticosteroids and other agents are typically used in women with alopecia areata. Because alopecia can be devastating to women, management should include an assessment for psychological effects. Propecia inhibits conversion of testosterone. Oral finasteride has been shown to be effective in the treatment of hair loss in men, while its efficacy in women has remained controversial. The patients self-assessment demonstrated that finasteride treatment decreased hair loss, increased hair growth and improved appearance of hair. These improvements were confirmed by investigator assessment and assessments of photographs. No adverse effects were noted. Oral finasteride may be effective for the treatment of pattern hair loss in postmenopausal women in the absence of clinical or laboratory signs of hyperandrogenism.Rogaine topical solution is widely used by adults for hair loss, but its use by adolescents has not been systematically evaluated. This article presents information on the efficacy and proper use of Rogaine topical solution in adolescent boys and girls.Topical application of minoxidil has limited success in treating male-pattern and female-pattern alopecia, but it’s unsuccessful in alopecia areata. Oral finasteride (Propecia) yields better results in both hair retention and new hair growth for some individuals. An alternate treatment is surgical redistribution of hair follicles by autografting.

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Patients with alopecia areata may be treated with topical corticosteroids, such as betamethasone dipropionate, halcinonide, and triamcinolone acetonide, or by intralesional injections, which may help to stimulate hair growth if hair loss is confined to small patches; this therapy may produce regrowth in 4 to 6 weeks. Hair loss that persists for more than 1 year has a poor prognosis for regrowth.Other drug therapy may include [order] photochemotherapy with methoxsalen and ultraviolet light, dermatomucosal agents such as anthralin, antibiotics for bacterial infections, and antifungal agents for fungal infections.
While topical solutions such as Rogaine® brand monoxidil have been used to treat hair loss, Propecia brand Finasteride by Merck & Company, Inc. is the only FDA approved pill approved for the prevention of hair loss and possible hair re-growth. Like Rogaine, Propecia was discovered when its generic equivalent being used for another purpose was found to have beneficial side effects [order online]. Finasteride is the generic name for the drug, which was already in existence for quite some time and had been produced under the name Proscar by Merck & Company and used for treatment of enlarged prostates, a syndrome medically called benign prostatic hyperplasia (BPH). BPH is caused by an overproduction of DHT, which causes the prostate to grow. Many BHP patients were also suffering with MPB, and when patients began taking Proscar®, they noticed the re-growth of hair also. This sparked new testing and the birth of Propecia® as a hair restoration drug. The approval of Propecia by the FDA was easy to achieve, since it was merely marketing already approved Finasteride as a hair restoration drug, with a much smaller dosage than that required for BPH.Side effects of Propecia in a few persons studied include diminished sex drive, difficulty in achieving an erection, and a decreased sperm production. Side effects were found in less than three percent of participants in clinical studies. Fortunately when the drug’s use was discontinued, the side effects went away and normal functions resumed. Of course there are some who say that the growth of new hair is worth the cost of a drop in libido. Only you can decide whether this side effect is worth the personal cost to you. Finasteride is metabolized primarily by the liver, and therefore anyone suffering with liver disease may not be able to take the drug, and should consult a physician [online order]. Additionally, as with Monoxidil, it can mask PSA levels, thus caution should be used if used by patients with elevated PSA levels, as it may be difficult to read levels properly when diagnosing potential prostate cancer. Of course proper consultation with your physician will help determine if taking Finasteride treatments such as Propecia is right for you.